KMID : 1035120190190020090
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Asian Oncology Nursing 2019 Volume.19 No. 2 p.90 ~ p.97
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Menopausal Symptoms and Quality of Life Among Breast Cancer Patients with Chemotherapy-induced Amenorrhea
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Park Jin-Hee
Jung Yong-Sik Kim Ji-Young Bae Sun-Hyoung Jo Yu-Jung
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Abstract
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Purpose: The aim of this study was to evaluate the severity of menopausal symptoms and their impact on the quality of life (QOL) in breast cancer patients with chemotherapy-induced amenorrhea.
Methods: A cross-sectional survey design was used. Participants were 112 breast cancer patients with chemotherapy-induced amenorrhea. They completed the Menopause Rating Scale (MRS) and the Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, independent ttests, one-way ANOVA, Pearson¡¯s correlation coefficients, and multiple regression with SPSS/WIN 23.0.
Results: The prevalence of symptoms among the participants were as follows: sleep problems, 88.4%; physical and mental exhaustion, 80.4%; joint and muscular discomfort, 76.8%; and depression, 70.5%. Menopausal symptoms had a significant negative association with QOL. The results of the regression analysis showed that psychological and urogenital symptoms were statistically significant in explaining patients¡¯ QOL and accounted for 70% of the total variance.
Conclusion: Menopausal symptoms appear to be a significant problem for premenopausal breast cancer patients. Assessment and control of menopausal symptoms played a large role in maintaining the quality of life in breast cancer patients.
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KEYWORD
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Breast neoplasms, Menopause, Quality of life, Drug therapy
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