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KMID : 1035120190190020090
Asian Oncology Nursing
2019 Volume.19 No. 2 p.90 ~ p.97
Menopausal Symptoms and Quality of Life Among Breast Cancer Patients with Chemotherapy-induced Amenorrhea
Park Jin-Hee

Jung Yong-Sik
Kim Ji-Young
Bae Sun-Hyoung
Jo Yu-Jung
Abstract
Purpose: The aim of this study was to evaluate the severity of menopausal symptoms and their impact on the quality of life (QOL) in breast cancer patients with chemotherapy-induced amenorrhea.

Methods: A cross-sectional survey design was used. Participants were 112 breast cancer patients with chemotherapy-induced amenorrhea. They completed the Menopause Rating Scale (MRS) and the Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, independent ttests, one-way ANOVA, Pearson¡¯s correlation coefficients, and multiple regression with SPSS/WIN 23.0.

Results: The prevalence of symptoms among the participants were as follows: sleep problems, 88.4%; physical and mental exhaustion, 80.4%; joint and muscular discomfort, 76.8%; and depression, 70.5%. Menopausal symptoms had a significant negative association with QOL. The results of the regression analysis showed that psychological and urogenital symptoms were statistically significant in explaining patients¡¯ QOL and accounted for 70% of the total variance.
Conclusion: Menopausal symptoms appear to be a significant problem for premenopausal breast cancer patients. Assessment and control of menopausal symptoms played a large role in maintaining the quality of life in breast cancer patients.
KEYWORD
Breast neoplasms, Menopause, Quality of life, Drug therapy
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